Hirofumi Ogura
Director
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Alcohol, smoking, and stress - in the body subjected to these irritants, the cells responsible for maintaining life seem to fight a war that never ends. Due to a severe shortage of workers, Red Blood Cell AA2153 has to quickly learn to deliver oxygen and collect carbon dioxide, even in dangerous conditions. Meanwhile, White Blood Cell U-1196 has to do her part by dealing with germs and viruses during life-threatening situations. In the midst of these crises, they have to work together to keep the body healthy, despite not knowing if their sacrifices will be worthwhile. Hataraku Saibou Black takes a different approach by showing the grittier side of the jobs our cells perform.
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Hirofumi Ogura
Director
Shoya Chiba
B Cell
Natsumi Fujiwara
Lactic Acid Bacteria (Panda)

Kana Hanazawa
Red Blood Cell (Erythrocite)

Saori Hayami
Regulatory T Cell

Kikuko Inoue
Macrophage

Akira Ishida
Cancer Cell
Yûsuke Kobayashi
Average Cell

Tomoaki Maeno
White Blood Cell (Neutrophil)
Maria Naganawa
Platelet
Mamiko Noto
Narrator

Daisuke Ono
Killer T Cell

Daisuke Ono
Memory T Cell

Rie Takahashi
Lactic Acid Bacteria (Red)
Toa Yukinari
NK Cell
Yuri Yoshida
Lactic Acid Bacteria (Black)
Yurika Kubo
Lactic Acid Bacteria (Spotted)
Akane Shimizu
Writer
Yuko Kakihara
Writer