Jim Carrey
Lloyd
20 years since their first adventure, Lloyd and Harry go on a road trip to find Harry's newly discovered daughter, who was given up for adoption.
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Jim Carrey
Lloyd
Jeff Daniels
Harry
Rob Riggle
Travis
Rob Riggle
Captain Lippincott
Laurie Holden
Adele
Rachel Melvin
Penny
Steve Tom
Dr. Pinchelow
Don Lake
Dr. Meldmann
Patricia French
Ms. Sourpuss
Elizabeth Cooper
Mrs. Julie James
Kathleen Turner
Fraida
Bill Murray
Ice Pick
Tembi Locke
Dr. Walcott
Paul Blackthorne
Emergency Room Doctor
Brady Bluhm
Billy
Eddie Shin
Gordy
Tommy Snider
Tom
Atkins Estimond
Gus
Lindsay Ayliffe
Professor Garabedian
